Tag Archive: anticoagulation

Oct 10

An analysis from the multicenter CORONOR registry has cautioned against aspirin use in the secondary prevention of cardiovascular events among stable CAD patients also taking oral anticoagulation.

An analysis from the multicenter CORONOR registry has cautioned against aspirin use in the secondary prevention of cardiovascular events among stable CAD patients also taking oral anticoagulation. The analysis suggested that the bleeding risk related to aspirin, in this specific setting, exceeds any benefits related to prevention of ischemic events. The findings were published October …

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Oct 06

An intravenous bolus of andexanet alfa immediately and significantly reversed the anticoagulation of apixaban in the ANNEXA-A study,

An intravenous bolus of andexanet alfa immediately and significantly reversed the anticoagulation of apixaban in the ANNEXA-A study, as per findings from the phase 3 study designed to test an antidote to the factor Xa inhibitor class of novel anticoagulants. The results of ANNEXA-A are slated for presentation on November 17, 2014 during the American …

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Apr 25

Maintaining warfarin anticoagulation appears safer than interrupting it for catheter–ablation procedures for atrial fibrillation

Maintaining warfarin anticoagulation appears safer than interrupting it for catheter–ablation procedures for atrial fibrillation, according to a randomized study involving >1500 patients at increased risk for thromboembolic stroke. The study authors noted that patients without periprocedural warfarin, bridged with low–molecular weight heparin in standard fashion, had >10–fold increased odds of ischemic stroke or transient ischemic …

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Apr 22

A recent study published in the April issue of JAMA Surgery has revealed that missed doses of prophylactic anticoagulation

A recent study published in the April issue of JAMA Surgery has revealed that missed doses of prophylactic anticoagulation account for about 24% of the deep vein thrombosis (DVT) that occurs in surgery and trauma patients. On the contrary, only 5% of those who took uninterrupted therapy reported a DVT.

Apr 18

Prophylactic anticoagulation is associated with decreased mortality in the ICU

Prophylactic anticoagulation is associated with decreased mortality in the ICU compared with mechanical devices for protection against venous thromboembolism (VTE), reported an observational study conducted at the UMass Memorial Medical Center, Worcester. While the anticoagulation therapy was associated with 19% lower risk of dying in the ICU and 16% lower risk of dying in the …

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Apr 14

Fibrinolytic therapy for intermediate risk pulmonary embolism prevents hemodynamic decompensation but augments the risk for major hemorrhage and stroke

Fibrinolytic therapy for intermediate risk pulmonary embolism prevents hemodynamic decompensation but augments the risk for major hemorrhage and stroke, reports a randomized, double–blind trial published April 9 in the New England Journal of Medicine. In patients with intermediate risk, routine anticoagulation for acute pulmonary embolism was sufficient since 7–day total mortality in these patients was …

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