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Jul 12

Analyzing the risk of atherosclerotic cardiovascular disease in individuals with familial hypercholesterolemia

Recently, an analysis was conducted in the individuals of the United States with a heterozygous familial hypercholesterolemia (FH) phenotype to determine the long-term risk of coronary heart disease (CHD) and total atherosclerotic cardiovascular disease (ASCVD). The FH phenotype was defined by a low-density lipoprotein (LDL) cholesterol concentration of ≥ 190 mg/dl while the referent value was less than 130 mg/dl. The results printed in the Circulation journal showed a considerable burden of the long-term ASCVD related to phenotypic FH. Thus, it is important to conduct FH screening for improving increased LDL concentrations, and in turn reducing CHD and ASCVD.

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