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Apr 06

A study presented at the American College of Cardiology 2014 Scientific Sessions states

A study presented at the American College of Cardiology 2014 Scientific Sessions states that metformin is of no help when given to patients without diabetes who had just suffered an ST–segment acute MI (STEMI). The drug does not preserve left ventricular ejection fraction [LVEF] after STEMI compared with placebo in those without diabetes. The study results revealed no significant difference in the primary end point, LVEF on MRI, between metformin–treated and placebo-treated subjects (53.1% vs 54.8%). NT–proBNP concentration did not differ between the 2 arms; it was 167 ng/L in both groups. The incidence of major adverse cardiac events (MACE) was 3.1% in the metformin group and 1.1% in the placebo group.

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