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Nov 15

AHA update:Vorapaxar Increases Bleeding in ACS

Giving a novel antiplatelet, vorapaxar, to acute coronary syndrome patients did not reduce mortality or serious cardiovascular events, but it did significantly increase the risk of major bleeding, including intracranial hemorrhage with a  35% increase in the relative risk of major bleeding events, and more than a three-fold increase in the risk of intracranial hemorrhage, said

Kenneth W. Mahaffey  of the Duke Clinical Research Institute in Durham, N.C., and colleagues. The trial was also published in NEJM.

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