Monthly Archive: February 2012

Feb 29

Some Weight-Loss Methods May Be Dangerous For Certain CKD Patients.

Overweight or obese people with chronic kidney disease (CKD) may suffer further kidney damage if they use certain weight-loss methods,” according to a study published online in the International Journal of Obesity. Weight-loss medications and high-protein diets are not recommended for people with chronic kidney disease because these methods may lead to further kidney damage.

Feb 29

Lipoprotein-Associated Phospholipase A2 Activity & Raised CVD Risk.

Results of a case-control study support the use of lipoprotein-associated phospholipase A2 (LpPLA2) activity, instead of mass, to identify individuals with increased cardiometabolic risk.” Researchers “found a positive association between LpPLA2 activity and incident cardiovascular disease (CVD) in a population with a high prevalence of obesity and diabetes, whereas LpPLA2 mass showed an inverse association …

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Feb 29

Lifestyle Changes May Result In “Modest” Waistline Reduction.

According to a study published online Feb. 27 in the Archives of Internal Medicine, “physicians’ efforts to improve their obese patients’ health by promoting lifestyle change might do better to embrace ‘a more realistic expectation': a modest reduction of patients’ waist circumference and the prevention of further weight gain.  

Feb 29

Afib May Lead to Memory Trouble

Atrial fibrillation seems to increase the risk of cognitive and functional decline, even in the absence of stroke, a post-hoc analysis of two randomized trials found. Nearly 10% of more than 31,000 patients had or developed atrial fibrillation, which was associated with a greater risk for cognitive decline, new dementia, loss of independence, and admission …

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Feb 29

An Orange a Day Keeps Stroke Away

Padma Shri and Dr B C Roy National Awardee Dr KK Aggarwal Flavanone in oranges, grapefruit, and other citrus fruit may modestly reduce stroke risk among women. Women with the highest levels of flavanone in their diet were 19% less likely to have an ischemic stroke during 14 years of follow-up than those with the …

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Feb 28

FDA Approves Once-A-Day Drug for Type 2 Diabetes

Merck announced on February 2 that the US Food and Drug Administration (FDA) has approved sitagliptin and metformin hydrochloride (HCl) extended-release tablets (Janumet XR) for treatment of type 2 diabetes.

Feb 28

Focus on CKD Patients With Highest SBP: KEEP

A new “real-world” study in chronic kidney disease (CKD) has found that high systolic blood pressure (SBP) seems to account for most of the progression to end-stage renal disease (ESRD) in these patients and that this risk starts at around 140 mm Hg, rather than at 130 mm Hg, said Dr Carmen A Peralta (University …

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Feb 28

Intravascular Ultrasound Improves TLR Outcomes of Bifurcation Lesions PCI

Long-term clinical outcomes (TLR target lesion revascularization) ) of percutaneous intervention of complex coronary bifurcation lesions are significantly better when the procedure is performed with adjunctive intravascular ultrasound (IVUS) guidance, according to a study reported in the American Journal of Cardiology online February 2.

Feb 28

Everolimus-Eluting Stent on Par With Sirolimus-Eluting Stent in CAD Patients

The everolimus-eluting stent and the sirolimus-eluting stent are equally safe and efficacious in patients with coronary artery disease, the SORT OUT IV Trial investigators reported online February 3 in Circulation by Dr. Lisette Okkels Jensen, from Odense University Hospital in Denmark, and colleagues. On intention-to-treat analysis at nine months, the rates of death, cardiac death, …

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Feb 28

FDA OKs First Drug-Eluting Stents for Use in MI

Padma Shri and Dr B C Roy National Awardee Dr KK Aggarwal Drug eluting stents have been used in diabetics and or Acute Mi as off label use up till now. With FDA approving specific stents in these conditions its legal implications are many. FDA OKs First Drug-Eluting Stents for Use in MI 1.    Drug-eluting …

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