Daily Archive: November 16, 2011

Nov 16

Cardiac stem cell update

The traditional view that the reparative ability of the heart is limited by the inability of terminally differentiated cardiomyocytes to undergo cell division after the first weeks of life has been challenged by recent studies suggesting that the heart is capable of limited self-regeneration. Current evidence suggests that there are at least four potential sources …

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Nov 16

The Balloon Jerk Sign a new predictor of Severe MR after Percutaneous Transluminal Mitral Commisurotomy

The sudden jump of the distally inflated balloon from LV to LA appears to be due to the continued traction applied to the balloon assembly by the operator and this may predispose to the development of MR. Satheesh S and group from  Departments of Cardiology and CTVS, JIPMER, Pondicherrysuggest that traction on the balloon should …

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Nov 16

AHA update:AIDA STEMI: No benefit of IC over IV abciximab

There was no benefit of giving abciximab by an intracoronary (IC) bolus over the normal IV route in the AIDA STEMI trial. Dr Holger Thiele (University of Leipzig, Germany) noted that the primary end point of the study, a composite of death/new MI/new heart failure at 90 days, was not different between the two groups, …

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Nov 16

AHA update:Whom not to bridge: Dental, cataract, and colonoscopy patients

Dr Samuel Z Goldhaber (Brigham and Women’s Hospital, Boston, MA) said that over 90% physicans bridge their patients. But there is a lack of evidence. There are no randomized clinical trials to say that bridging is the way to go. Thromboembolism (TE) is uncommon in low- or intermediate-risk patients interrupting warfarin for five days or …

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Nov 16

Put all patients with CAD on statins

In patients with CHD or a CHD risk equivalent who can tolerate statin therapy one should start treatment with at least a moderate dose of a statin (eg, 40 mg of lovastatin, pravastatin, or simvastatin, 20 mg of atorvastatin, or 5 to 10 mg of rosuvastatin) independent of the baseline LDL-C. Even if you choose LDL-goal-based strategy of lipid management, and …

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Nov 16

Facts and figures in cardiology

CAD is present in rural (3-5%) and urban (7-10%) populations. There could be 30 million CAD patients in India of which 14 million are in urban and 16 million in rural areas (Circulation 1998, 97: 596-601).