Mar 11

Alirocumab shows significantly better LDL-C lowering than ezetimibe, with a comparable safety profile to ezetimibe

this is testing

Feb 10

Researchers have determined that two mutations on a single gene can interact in a way that lowers the carrier’s risk for a heart attack.

Researchers have determined that two mutations on a single gene can interact in a way that lowers the carrier’s risk for a heart attack. The variants are found in a gene called DBH, which regulates an enzyme involved in the conversion of dopamine to norepinephrine. The research is published in a recent issue of the journal Circulation Research.

Feb 09

Waiting until a patient’s systolic blood pressure exceeds 150 mm Hg before intensifying antihypertensive medication

Waiting until a patient’s systolic blood pressure exceeds 150 mm Hg before intensifying antihypertensive medication is associated with an increased risk of acute cardiovascular events and death, according to the results of a large analysis published in the BMJ.

Feb 06

Baseline and serial measures of high-sensitivity cardiac troponin T (hs-TnT)

Baseline and serial measures of high-sensitivity cardiac troponin T (hs-TnT) predict incident atrial fibrillation independently of traditional risk factors, suggests a new analysis from the Cardiovascular Health Study (CHS), published online in Heart Rhythm.

Feb 05

There seem to be no significant differences in pregnancy loss, need for high-level neonatal care

There seem to be no significant differences in pregnancy loss, need for high-level neonatal care, or overall maternal complications in women with mild-to-moderate hypertension at 14 to 33 weeks gestation randomized to tight vs. “less-tight” BP control, suggested an international trial. However, women assigned to tight BP control were significantly less likely to develop severe hypertension. The report is published online in the New England Journal of Medicine.

Feb 03

Use of a high-sensitivity troponin (hs-Tn) assay and sex-specific diagnostic thresholds doubles the number of MI diagnoses in women presenting with ACS

Use of a high-sensitivity troponin (hs-Tn) assay and sex-specific diagnostic thresholds doubles the number of MI diagnoses in women presenting with ACS, suggests a prospective study that also suggested women are less likely to receive evidence-based treatment than men despite the same diagnosis. The report is published online in the BMJ.

Feb 02

Medtronic plc has revealed new one-year clinical data showing that transcatheter aortic valve replacement (TAVR)

Medtronic plc has revealed new one-year clinical data showing that transcatheter aortic valve replacement (TAVR) with the self-expanding CoreValve System offers advantages in survival and safety compared to surgical aortic valve replacement (SAVR) in high risk aortic stenosis patients who have previously undergone coronary artery bypass grafting (CABG) surgery. The findings were presented at the 2015 Annual Meeting of The Society of Thoracic Surgeons (STS).

Feb 02

Medtronic plc has revealed new one-year clinical data showing that transcatheter aortic valve replacement (TAVR)

Medtronic plc has revealed new one-year clinical data showing that transcatheter aortic valve replacement (TAVR) with the self-expanding CoreValve System offers advantages in survival and safety compared to surgical aortic valve replacement (SAVR) in high risk aortic stenosis patients who have previously undergone coronary artery bypass grafting (CABG) surgery. The findings were presented at the 2015 Annual Meeting of The Society of Thoracic Surgeons (STS).

Jan 31

The full implementation of the Eighth Joint National Committee (JNC 8)

The full implementation of the Eighth Joint National Committee (JNC 8) guidelines for the management of adult hypertension could prevent approximately 56 000 cardiovascular events and 13 000 deaths each year in the US, without increasing costs to the healthcare system, points a new analysis published January 28 in the New England Journal of Medicine.

Jan 28

Fifty-five-year-olds who had prolonged moderately elevated non–HDL-cholesterol levels (>160 mg/dL)

Fifty-five-year-olds who had prolonged moderately elevated non–HDL-cholesterol levels (>160 mg/dL) when they were young adults had higher odds than their peers to have coronary heart disease by the time they were 70, suggested an analysis based on the Framingham Offspring Cohort, published online January 26 in Circulation.

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